Custom Peptides
Cayman Chemical Guafensn 10mg
An analytical reference standard categorized as an expectorant; intended for use in analytical forensic applications
Cayman Chemical 1 3DIdocosnoyl2Oleoyl Gly 10mg
A triacylglycerol; has been found in cocoa butter; increases the solidification rate of and prevents fat bloom formation on dark chocolate when used as a seed material
Cayman Chemical dgwota cysnta Tlosd 10mg
A flavonoid glycoside with diverse biological activities; inhibits CAVII (Ki = 4.6 nM); scavenges DPPH and superoxide radicals (IC50s = 12.8 and 42 µM, respectively); cytotoxic to Jurkat, HepG2, and COLO 205 cells (IC50s = 11.6, 14.3, and 55.4 µM, respectively); reduces TPA-induced EAr edema (ID50 = 0.357 mg/ear); decreases triglyceride accumulation in the liver and skeletal muscle in high-fat diet-fed KKAy diabetic mice at 100 mg/kg
Cayman Chemical AurntIobtusIn 10mg
An anthraquinone with diverse biological activities; inhibits RLAR in vitro (IC50 = 13.6 μM); activates the AhR at 10 and 100 μM; inhibits arachidonic acid-, ADP-, and collagen-induced rat platelet aggregation; induces vasorelaxation in isolated precontracted rat mesenteric artery rings
Cayman Chemical 1 2DIoleoyl3MyrIstoylrac 10mg
A triacylglycerol; has been found in the fat body of male B. lapidarius bumblebees and in R. erythropolis bacteria utilizing phenol or succinic acid as a carbon source
Cayman Chemical ACTH4-11humnmousera 10mg
A peptide fragment of ACTH; induces differentiation of melanocytes at 1,000 nM; inhibits ACE activity in homogenized canine lung (IC50 = 24 µM); has been used to determine substrate specificity of recombinant CPBHz
Cayman Chemical 1 2DIpalmItoyl3LInoleoylr 10mg
A triacylglycerol; has been found in ostrich and emu oils and bovine milk fat
Cayman Chemical CephalomnIn 10mg
A taxane diterpenoid; inhibits calcium-induced microtubule depolymerization in vitro; increases vincristine accumulation in multidrug-resistant 2780AD ovarian cancer cells
Cayman Chemical 9 10DIhydroxystearIc AcId 10mg
An oxidation product of oleic acid; can be formed from oleic acid in HepG2 cells; activates PPARα in CV-1 cells at 50-100 µM; decreases blood glucose levels, increases insulin sensitivity, and decreases body weight in high-fat diet-fed KKAy diabetic mice at 4% in the diet
Cayman Chemical LIthospermIc AcId 10mg
A polyphenol; inhibits xanthine oxidase (IC50 = 5.2 UG/ml); scavenges DPPH radicals (IC50 = 23.2 UG/ml); inhibits ROS production from PMA-stimulated isolated human neutrophils in a concentration-dependent manner; inhibits 3'-processing and 3'-joining to target DNA by HIV-1 integrase (IC50s = 0.83 and 0.48 µM, respectively); inhibits acute HIV-1 infection of H9 human lymphoma cells (IC50 = 2 µM) without inducing cytotoxicity; prevents carbon tetrachloride-induced hepatic necrosis in mice at 100 mg/kg
Cayman Chemical Zopolrestat 10mg
A potent aldose reductase inhibitor (IC50s = 1.9 and 41 nM for the human placenta and rat lens enzymes, respectively); inhibits sorbitol accumulation in human and rat erythrocytes (IC50s = 370 and 220 nM, respectively); inhibits ethanol-induced aldose reductase activity and lipid accumulation in HepG2 cells at 50 μM; reduces sciatic nerve, retina, and lens accumulation of sorbitol in a rat model of STZ-induced diabetes at 50 mg/kg; reduces protein excretion and maintains lens transparency and myo-inositol content in rats with STZ-induced diabetes at 100 mg/kg; inhibits GLOI (Ki = 18 μM)
Cayman Chemical 4 5-DIcaffeoylquInIc AcId 10mg
A polyphenol with diverse biological activities; inhibits HIV-1 integrase 3' end processing, 3’ end joining, and disintegration (IC50s = 0.13, 0.24, and 0.3 μg/ml, respectively); inhibits HIV-1 replication in MT-2 T lymphoblastoid cells (EC50 = 2 UG/ml); scavenges DPPH radicals in a cell-free assay (IC50 = 19.8 µM) and inhibits superoxide production in human neutrophils activated by fMLF and cytochalasin B (IC50 = 1.49 µM); decreases PGE2 production in LPS-stimulated U937 cells at 5 and 10 UG/ml but increases it at 200 UG/ml and increases TNF-α production at 5-200 UG/ml; inhibits melanogenesis by 84% and decreases the levels of proteins involved in melanin biosynthesis in B16F1 murine melanocytes at 25 µM
Cayman Chemical 2CLOroN6Cyclopentyladenos 10mg
An adenosine receptor agonist; binds selectively to A1 over A2A and A3 receptors (Kis = 0.83, 2,300 and 42 nM, respectively, for the human receptors expressed in CHO cells; decreases heart rate in isolated rat atria (EC50 = 8.2 nM) but does not affect vasodilation in bovine coronary arteries; inhibits isoniazid- and pentylenetetrazole-induced convulsions in mice at 8.3 μmol/kg
Cayman Chemical MetrIzamIde 10mg
A non-ionic contrast agent; does not induce EEG abnormalities in rabbits at 0.1 ml/kg of a 370 mg I/ml solution; has been used as a solute in gradient centrifugation applications