Custom Peptides
Cayman Chemical LognIc AcId 10mg
An iridoid glycoside; stimulates GLP-1 secretion by NCI H716 human enteroendocrine colorectal cancer cells at 1 μM; inhibits dexamethasone-, 3-isobutyl-1-methylxanthine-, and insulin-induced differentiation of mouse 3T3-L1 fibroblasts into adipocytes at 10 μg/ml; decreases the plasma atherogenic index and cardiac risk ratio, as well as plasma levels of IL-6, TNF-α, and oxLDL in a cholesterol-rich diet-induced rabbit model of atherosclerosis
Cayman Chemical CalcItonInel 10mg
A peptide hormone that lowers blood calcium levels and inhibits bone resorption; binds to CTR2 with higher affinity than human, porcine, or rat calcitonin (Kis = 0.01, 2.95, 0.44, and 5.89 nM, respectively, in radioligand binding assays); inhibits gastric emptying more potently than human calcitonin in conscious dogs at 10 UG/kg; increases the paw withdrawal threshold in a mouse model of carrageenan-induced inflammation at 0.2 UG/paw
Cayman Chemical Polygalae radx Tenufoln 10mg
A saponin with neuroprotective activity; inhibits BACE activity by 54.4% at 10 μg/ml; inhibits secretion of Aβ40 and Aβ42 from COS-7 cells expressing APP695 WT or APP695 Swe at 2 μg/ml; prevents decreases in PC12 cell viability induced by Aβ (25-35) at 20 and 40 μg/L; inhibits increases in the escape latency and total swimming distance induced by Aβ (25-35) in the Morris water maze in mice at 3 and 9 mg/kg
Cayman Chemical VItexIn-4-O-glucosIde 10mg
A flavonoid glycoside with antioxidant activity; reduces tertbutyl hydroperoxide-induced DNA damage, lipid peroxidation, and cell death in ECV304 cells from 16-128 µM
Cayman Chemical ACtoACtylCoenzyme AsodIu 10mg
A precursor to HMG-CoA in the isoprenoid pathway; reversibly converted to acetyl-CoA by acetoacetyl-CoA thiolase
Cayman Chemical ImepIphydrobromIde 10mg
A histamine H3 receptor agonist (KI = 0.4 nM in SK-N-MC cell membranes expressing the human receptor); selective for histamine H3 over H1 and H2 receptors in CHO cell membranes expressing the guinea pig and human receptors, respectively (Kis = >16 μM for both) but also agonizes H4 receptors (KI = 9 nM in SK-N-MC cell membranes expressing the human receptor); decreases hypothalamic histamine release in anesthetized rats at 5 mg/kg; decreases flinching in the formalin test in rats at 5 and 30 mg/kg and inhibits formalin-induced paw edema at 30 mg/kg
Cayman Chemical 9 Z 11 E 13 ZOctadecatrIe 10mg
A fatty acid methyl ester; isomer of 9(Z),11(E),13(E)-octadecatrienoic acid methyl ester; has been used as a standard for the quantification of 9(Z),11(E),13(Z)-octadecatrienoic acid in wild growing pomegranate seed oil
Cayman Chemical CosyntropInacetate 10mg
A synthetic form of ACTH 1-24; increases plasma concentration of hydrocortisone in mares more rapidly and consistently than natural ACTH 1-24
Cayman Chemical HeptadecnoylLcarnItInd3 10mg
An internal standard for the quantification of heptadecanoyl-L-carnitine by GC- or LC-MS
Cayman Chemical BepotastInbesylate 10mg
A histamine H1 receptor antagonist; selective over H3, α1-, α2-, and β-adrenergic, dopamine D2long, serotonin 5-HT2, muscarinic acetylcholine, and benzodiazepine receptors; reduces dye leakage from the nasal passages of sensitized rats (ED50 = 0.03 mg/kg); inhibits histamine-induced bronchoconstriction in the anesthetized dog (ED50 = 3.2 UG/kg); dose-dependently prevents conjunctival vascular hyperpermeability a in guinea pig model of conjunctivitis
Cayman Chemical SGernylgernylLglutathIon 10mg
A P2RY8 ligand; selectively induces internalization of P2RY8 over S1P2, GPR55, CysLT1 receptor, and CysLT2 receptor at 100 nM; inhibits CXCL12-induced migration of P2RY8-expressing WEHI-231 B cell lymphoma cells and isolated human tonsil germinal center B cells at 10 nM
Cayman Chemical SIsunatovIr 10mg
An RSV fusion inhibitor (IC50 = 0.9 nM); reduces RSV A2 replication in a plaque reduction assay in vitro (EC50 = 1.3 nM); decreases lung viral titers in a mouse model of RSV infection at 1, 10, or 50 mg/kg
Cayman Chemical 4ChLRomethcathInonhydroc 10mg
An analog of methcathinone that has a chlorine atom inserted at the 4 position of the phenyl ring; intended for forensic and research applications
Cayman Chemical VoxIlaprevIr 10mg
A pan-genotypic HCV NS3/4A protease inhibitor; inhibits replication of wild-type HCV genotypes 1a, 1b, 2a, 2b, 3a, 4a, 5a, and 6a (EC50s = 1.9-6.6 nM in replicon assays); inhibits replication of mutant HCV genotypes containing NS3 resistance-associated substitutions (EC50s = 3.1, 2.7, and 4 nM for HCV genotypes 1a Q80K, 1a R155K, and 1b D168E, respectively)